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A Model Context Protocol (MCP) server that provides comprehensive access to the UCSC Genome Browser API. This server enables LLM applications to query genomic data, sequences, tracks, and metadata from the UCSC Genome Browser.
This MCP server exposes 12 tools that cover all major UCSC Genome Browser API endpoints:
Listing & Discovery Tools
- find_genome - Search for genomes using keywords, accession IDs, or organism names
- list_public_hubs - List all available public track hubs
- list_ucsc_genomes - List all UCSC database genomes
- list_genark_genomes - List GenArk assembly hub genomes
- list_hub_genomes - List genomes from a specific hub
- list_files - List downloadable files for a genome
- list_tracks - List data tracks in a genome or hub
- list_chromosomes - List chromosomes in a genome or track
- list_schema - Get schema/field definitions for a track
Data Retrieval Tools
- get_sequence - Retrieve DNA sequences from genomes
- get_track_data - Get track data (genes, variants, annotations, etc.)
- search_genome - Search within a genome assembly
Works with Claude (desktop and mobile), Cursor, Windsurf, VS Code, and any MCP-compatible AI app.
Category: Developer Tools
Don't lose this
Three weeks from now, you'll want hlydecker/ucsc-genome-mcp again. Will you remember where to find it?
Save it to your library and the next time you need hlydecker/ucsc-genome-mcp, it’s one tap away — from any AI app you use. Group it into a bench with the rest of the team for that kind of task and you can pull the whole stack at once.
⚡ Pro tip for geeks: add a-gnt 🤵🏻♂️ as a custom connector in Claude or a custom GPT in ChatGPT — one click and your library is right there in the chat. Or, if you’re in an editor, install the a-gnt MCP server and say “use my [bench name]” in Claude Code, Cursor, VS Code, or Windsurf.
a-gnt's Take
Our honest review
This plugs directly into your AI and gives it new abilities it didn't have before. hlydecker/ucsc-genome-mcp. Once connected, just ask your AI to use it. It's completely free and works across most major AI apps. This one just landed in the catalog — worth trying while it's fresh.
Tips for getting started
Tap "Get" above, pick your AI app, and follow the steps. Most installs take under 30 seconds.
What's New
Imported from awesome:punkpeye/awesome-mcp-servers
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